![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png){kind=small}
mstislavlобрезание сокращает риск ВИЧ-инфекции на 50%.
ирония судьбы: десятки институтов работают над вакциной, а простейшая хирургическая процедура эффективней.
circumcision reduces risk of HIV-infection by 50%
ирония судьбы: десятки институтов работают над вакциной, а простейшая хирургическая процедура эффективней.
circumcision reduces risk of HIV-infection by 50%
![[identity profile]](https://www.dreamwidth.org/img/silk/identity/openid.png){kind=small}
знаю, знаю...
Date: 2006-12-18 06:36 am (UTC)no subject
Date: 2006-12-18 07:07 pm (UTC)no subject
Date: 2006-12-18 07:59 pm (UTC)thre is no need to get personal
Date: 2006-12-18 08:29 pm (UTC)хотя это аргумент: бояться увеличения числа инфицированных после обрезания не нужно, мужики просто побояться. as you wish.
ps я предпочитаю обращение на вы
no subject
Date: 2006-12-19 03:42 pm (UTC)Three trials of circumcision have now been cut short
1) Похоже, проверяли только на чернокожих. Прежде чем толкать такую статью, нужно было бы провести исследования на других расах
2) Непонятно, устранялась ли возможная причина "обрезанные мальчики скорей всего из более религиозных семей и потому реже трахаются направо и налево"
no subject
Date: 2006-12-20 12:38 pm (UTC)Auvert B,
Taljaard D,
Lagarde E,
Sobngwi-Tambekou J,
Sitta R,
Puren A.
Hopital Ambroise-Pare, Assitance Publique-Hopitaux de Paris, Boulogne, France. bertran.auvert@apr.aphp.fr
BACKGROUND: Observational studies suggest that male circumcision may provide protection against HIV-1 infection. A randomized, controlled intervention trial was conducted in a general population of South Africa to test this hypothesis. METHODS AND FINDINGS: A total of 3,274 uncircumcised men, aged 18-24 y, were randomized to a control or an intervention group with follow-up visits at months 3, 12, and 21. Male circumcision was offered to the intervention group immediately after randomization and to the control group at the end of the follow-up. The grouped censored data were analyzed in intention-to-treat, univariate and multivariate, analyses, using piecewise exponential, proportional hazards models. Rate ratios (RR) of HIV incidence were determined with 95% CI. Protection against HIV infection was calculated as 1 - RR. The trial was stopped at the interim analysis, and the mean (interquartile range) follow-up was 18.1 mo (13.0-21.0) when the data were analyzed. There were 20 HIV infections (incidence rate = 0.85 per 100 person-years) in the intervention group and 49 (2.1 per 100 person-years) in the control group, corresponding to an RR of 0.40 (95% CI: 0.24%-0.68%; p < 0.001). This RR corresponds to a protection of 60% (95% CI: 32%-76%). When controlling for behavioural factors, including sexual behaviour that increased slightly in the intervention group, condom use, and health-seeking behaviour, the protection was of 61% (95% CI: 34%-77%). CONCLUSION: Male circumcision provides a degree of protection against acquiring HIV infection, equivalent to what a vaccine of high efficacy would have achieved. Male circumcision may provide an important way of reducing the spread of HIV infection in sub-Saharan Africa. (Preliminary and partial results were presented at the International AIDS Society 2005 Conference, on 26 July 2005, in Rio de Janeiro, Brazil.).
no subject
Date: 2006-12-20 12:39 pm (UTC)2) исследование проводилось на необрезанных мужчинах, рандомизированно. то есть в начале и контрольнаяи экспериментальная группа были необрезаны.
подробности здесь
на самом деле это на поверхность всплыла сверхушка айсберга похожих исследований, которые проводятся уже в течение как минимум 6 лет.
no subject
Date: 2006-12-20 01:29 pm (UTC)Такой большой разброс 95% CI: 32%-76% - это типично для подобных исследований?
no subject
Date: 2006-12-20 01:33 pm (UTC)